Infertility is a disease recognized by the World Health Organization (WHO) that affects those couples who are unable to conceive naturally after a year of frequent sexual intercourse without using contraceptive methods. Between 48 million couples and 186 million people have infertility in the world.
As announced by Eugin, coinciding with the month of fertility that is celebrated this June, in its assisted reproduction and fertility centers, the rates of multiple pregnancies in in vitro fertilization (IVF) treatments using donor eggs have been reduced, going from 10-11% in 2018 to 1-1.5% in 2021. In the case of treatments with oocytes from the patient herself, this figure has also registered a notable decrease, so that twin pregnancies have gone from 15% to just under 5% in the same period.
This improvement occurs thanks to the implementation of a policy of elective transfer of a single embryo together with the extensive use of Embryoscope incubators, which employ «time lapse» technology and carry out uninterrupted monitoring of the embryo through continuous image captures. This technology allows observing the evolution of the embryos in the incubators themselves and offers more detailed information of great value to embryologists.
Elective single embryo transfer
Within the framework of the IVF process, one of the decisions involves deciding to transfer a single embryo or two. Elective single embryo transfer reduces multiple pregnancies during one treatment and the procedure is performed electively when multiple embryos are available.
In a multiple pregnancy, the risks of complications for the fetus and the mother are increased, including gestational diabetes, preeclampsia and premature delivery. To prevent multiple births, the embryologist selects the embryo based on its general appearance, number of cells, and quality, and places it in the uterus in the hope of achieving a pregnancy. The procedure is carried out during the multicellular embryonic stage (day 3) or during the blastocyst stage (days 5/6).
«Before, it was necessary to extract the embryos from the incubator to observe them under a microscope, define the morphological characteristics and decide the best moment for the transfer. We now have incubators with a built-in camera that follow the development of the embryos 24 hours a day, and that offer us valuable data for embryo selection”, underlines the director of the Eugin Barcelona Laboratory, María José Zamora.
Thanks to embryo culture exclusively in “time lapse” incubators, embryo transfer on day 5 of development, that is, at the blastocyst stage, instead of on day 3, has become widespread. » allows embryologists to observe important events and characteristics of the embryo that may go unnoticed in conventional static observations, and to select the embryo with the greatest implantation potential.
The average number of embryos transferred per cycle in 2018, according to data from the registry of the Spanish Fertility Society (SEF), was 1.3 in IVF with donor eggs and 1.6 in IVF with the patient’s own eggs. At Eugin, this figure was 1.35 for IVF with donor oocytes and 1.8 with own ovules. In 2021, the average number of embryos transferred decreased to 1.04 and 1.4, respectively.
#World #Fertility #Day #predicts #probability #pregnancy