A group of researchers from Chalmers University of Technology in Sweden have created a spray that can fight infections and “kill” antibiotic-resistant bacteria, responsible for the deaths of 1.3 million people worldwide each year. .
“Our innovation can have a double impact in the fight against antibiotic resistance. The material has been shown to be effective against many different types of bacteria, including those that are resistant to antibiotics, such as methicillin-resistant Staphylococcus aureus (MRSA), while also having the potential to prevent infection and, therefore, reduce the need for antibiotics”, the experts have commented.
The material consists of small hydrogel particles equipped with a type of peptide that effectively kills and binds to bacteria, thus providing a protective environment and increasing the stability of the peptides. This, in turn, allows them to work together with bodily fluids such as blood, which otherwise inactivates the peptides, making them difficult to use in healthcare.
In previous studies, the researchers showed how the peptides can be used for wound care materials, such as wound dressings. They have now published two new studies in which the bactericidal material is used as a spray for wounds and as a coating on medical devices that are inserted into the body. This new step in research means the innovation can be used in more ways and be even more beneficial in healthcare.
“The substance in this wound spray is non-toxic and does not affect human cells. Unlike existing bactericidal sprays, it does not inhibit the body’s healing process. The materials, which are simply sprayed on the wound, can also kill bacteria in less time,” the experts stressed.
